微波水热法制备氧化镁-氧化铜-氧化钙复合材料及其抗菌性能

doi:10.11962/1006-4990.2020-0070

摘要/Abstract

摘要：

以氯化镁、氯化铜、氯化钙为原料,十六烷基三甲基溴化铵（CTAB）为分散剂,采用微波水热法合成了氧化镁-氧化铜-氧化钙复合材料;通过X射线衍射（XRD）、扫描电镜（SEM）、氮吸附（BET）等表征手段对样品进行了结构表征;利用最小抑菌浓度（MIC）和菌落计数法对样品的抗菌性能进行了研究。实验结果表明：氧化镁-氧化铜-氧化钙复合物具有纳米片状结构,制备的MgO_0.7CuO_0.1CaO_0.2比表面积为66.789 m²/g,平均孔径为54.117 nm,孔容为0.904 cm³/（g·nm）;MgO_0.7CuO_0.1CaO_0.2在质量浓度为500 μg/mL条件下展现出良好的抗菌性能,在质量浓度为600 μg/mL以上时抑菌率达到99.9%以上。

关键词: 氧化镁, 复合材料, 微波水热, 抗菌

Abstract:

MgO-CuO-CaO composites were synthesized by microwave hydrothermal using MgCl₂·6H₂O,CuCl₂·2H₂O and CaCl₂ as raw materials and CTAB as dispersant.The structures of the samples were characterized by X-ray diffraction（XRD）,scanning electron microscopy（SEM）,nitrogen adsorption（BET） and other characterization methods.The minimal inhibitory concentration（MIC） and colony count method were used to test the antibacterial properties of the samples.The results showed that MgO-CuO-CaO composites were nanoflake structure.The prepared MgO_0.7CuO_0.1CaO_0.2 had a specific surface area of 66.789 m²/g,an average pore diameter of 54.117 nm and a pore volume of 0.904 cm³/（g·nm）.MgO_0.7CuO_0.1CaO_0.2 showed excellent antibacterial properties at the concentration of 500 μg/mL,and the antibacterial rate reached more than 99.9% at the concentration of 600 μg/mL.

Key words: magnesium oxide, composite materials, microwave hydrothermal, antibacterial

中图分类号:

TQ132.2

田其哲,叶俊伟,宁桂玲. 微波水热法制备氧化镁-氧化铜-氧化钙复合材料及其抗菌性能[J]. 无机盐工业, 2020, 52(12): 12-16.

Tian Qizhe,Ye Junwei,Ning Guiling. Preparation and antibacterial properties of MgO-CuO-CaO composite by microwave hydrothermal method[J]. Inorganic Chemicals Industry, 2020, 52(12): 12-16.

图/表 6

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参考文献 24

[1]	Baker K S, Dallman T J, Field N, et al. Horizontal antimicrobial re-sistance transfer drives epidemics of multiple shigella species[J]. Nature Communications, 2018,9(1):1462.
[2]	Xin Q, Shah H, Nawaz A, et al. Antibacterial carbon-based nanoma-terials[J]. Adv.Mater., 2019,31(45):1804838.
[3]	Morris D E, Cleary D W, Clarke S C. Secondary bacterial infections associated with influenza pandemics[J]. Front Microbiol, 2017,8:1041.
[4]	Ding X, Duan S, Ding X, et al. Versatile antibacterial materials:An emerging arsenal for combatting bacterial pathogens[J]. Advanced Functional Materials, 2018,28(40):1802140.
[5]	Dadi R, Azouani R, Traore M, et al. Antibacterial activity of ZnO and CuO nanoparticles against gram positive and gram negative strains[J]. Mater Sci Eng C Mater Biol Appl, 2019,104:109968.
[6]	Wu W, Zhao W, Wu Y, et al. Antibacterial behaviors of Cu₂O particles with controllable morphologies in acrylic coatings[J]. Applied Surface Science, 2019,465:279-287.
[7]	Qi Y, Ye J, Zhang S, et al. Controllable synjournal of transition metal ion-doped CeO(2) micro/nanostructures for improving photocatalytic performance[J]. Journal of Alloys and Compounds, 2019,782:780-788.
[8]	叶俊伟, 杨瑶瑶, 陈弋心, 等. 纳米氧化镁抗菌材料的研究进展[J]. 化工进展, 2018,37(04):1460-1467.
[9]	El-Shaer A, Abdelfatah M, Mahmoud K R, et al. Correlation between photoluminescence and positron annihilation lifetime spectroscopy to characterize defects in calcined MgO nanoparticles as a first step to explain antibacterial activity[J]. Journal of Alloys and Compounds, 2020,817:8.
[10]	Li Y, Zhang W, Niu J, et al. Mechanism of photogenerated reactive oxygen species and correlation with the antibacterial properties of engineered metal-oxide nanoparticles[J]. ACS Nano, 2012,6(6):5164-5173.
[11]	Tang Z-X, Yu Z, Zhang Z-L, et al. Sonication-assisted preparation of CaO nanoparticles for antibacterial agents[J]. Química Nova, 2013,36(7):933-936.
[12]	Ngo D T, Sooknoi T, Resasco D E. Improving stability of cyclopentanone aldol condensation MgO-based catalysts by surface hydrophobization with organosilanes[J]. Applied Catalysis B:Environmental, 2018,237:835-843.
[13]	Deepthi N H, Vidya Y S, Anantharaju K S, et al. Optical,electrical and luminescent studies of CuO/MgO nanocomposites synthesized via sonochemical method[J]. Journal of Alloys and Compounds, 2019,786:855-866.
[14]	Krishnamoorthy K, Moon J Y, Hyun H B, et al. Mechanistic investiga-tion on the toxicity of MgO nanoparticles toward cancer cells[J]. Journal of Materials Chemistry, 2012,22(47):24610-24617.
[15]	柴政泽, 叶俊伟, 田其哲, 等. 气溶胶辅助法合成球形氧化镁及其吸附性能研究[J]. 无机盐工业, 2020,52(01):39-43.
[16]	Krishnamoorthy K, Manivannan G, Kim S J, et al. Antibacterial activity of MgO nanoparticles based on lipid peroxidation by oxygen vacancy[J]. Journal of Nanoparticle Research, 2012,14(9):1063.
[17]	Chang Y-N, Ou X-M, Zeng G-M, et al. Synjournal of magnetic graphene oxide-TiO₂ and their antibacterial properties under solar irradiation[J]. Applied Surface Science, 2015,343:1-10.
[18]	Makhluf S, Dror R, Nitzan Y, et al. Microwave-assisted synjournal of nanocrystalline MgO and its use as a bacteriocide[J]. Advanced Functional Materials, 2005,15(10):1708-1715.
[19]	Anicic N, Vukomanovic M, Koklic T, et al. Fewer defects in the surface slows the hydrolysis rate,decreases the ROS generation potential,and improves the non-ros antimicrobial activity of MgO[J]. Small, 2018,14(26):1800205.
[20]	Chai Z, Tian Q, Ye J, et al. Hierarchical magnesium oxide microspheres for removal of heavy ions from water and efficient bacterial inactivation[J]. Journal of Materials Science, 2020,55(10):4408-4419.
[21]	Abed C, Ali M B, Addad A, et al. Growth,structural and optical properties of ZnO-ZnMgO-MgO nanocomposites and their photocatalytic activity under sunlight irradiation[J]. Materials Research Bulletin, 2019,110:230-238.
[22]	Yamamoto O, Sawai J, Sasamoto T. Change in antibacterial characteristics with doping amount of ZnO in MgO-ZnO solid solution[J]. International Journal of Inorganic Materials, 2000,2(5):451-454.
[23]	Hong W, Meng M, Liu Q, et al. Antibacterial and photocatalytic properties of Cu₂O/ZnO composite film synthesized by electrodepo-sition[J]. Research on Chemical Intermediates, 2016,43(4):2517-2528.
[24]	Karthik K, Dhanuskodi S, Gobinath C, et al. Ultrasonic-assisted CdO-MgO nanocomposite for multifunctional applications[J]. Ma-terials Technology, 2019,34(7):403-414.

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