Abstract: By researching on chloridizing leaching process of antimony from the low grade multi-metal Sb-Pb sulphide ore， the optimum conditions were obtained as follows: the amount of chlorine gas was 1.2 times of theoretical amount，leaching temperature was 90 ℃，leaching time was 4 h，and ratio of liquid to solid was 4 mL/g.The leaching rate of antimony was 99.5% under the optimum conditons，and no significant change of leaching rate of antimony was found in the 4 times of recycled leaching liquid.The technology could solve the problem of multiple metal separation of multi-metal Sb-Pb sulphide ore other than mineral separation，and realized the separation of antimony in the process of chloridizing leaching，mineral resources will get comprehensive utilization greatly，and it was beneficial to facilitate the comprehensive development and utilization of resources and environmental protection.

Key words: multi-metal Sb-Pb sulphide ore, chloridizing leaching, antimony, separation