无机盐工业
主管:中海油天津化工研究设计院有限公司
主办:中海油天津化工研究设计院有限公司
   中海油炼油化工科学研究院(北京)有限公司
   中国化工学会无机酸碱盐专业委员会
ISSN 1006-4990 CN 12-1069/TQ

无机盐工业 ›› 2013, Vol. 45 ›› Issue (1): 10-.

• 论文 • 上一篇    下一篇

苯扎溴铵/二氧化硅杂化抗菌

刘海弟,岳仁亮,张婧坤,李伟曼,陈运法   

  1. 中国科学院过程工程研究所多相复杂系统国家重点实验室,北京 100190
  • 发布日期:2013-01-15

Preparation of benzalkonium bromide/silica composite antibacterial material and investigation on performance thereof

 LIU  Hai-Di, YUE  Ren-Liang, ZHANG  Jing-Kun, LI  Wei-Man, CHEN  Yun-Fa   

  1. State Key Laboratory of Multiphase Complex Systems,Institute of Process Engineering,
    Chinese Academy of Sciences,Beijing 100190,China
  • Online:2013-01-15

摘要: 研究了以碱性硅溶胶、十二烷基二甲基苄基溴化铵为原料,通过共沉淀制备杂化抗菌材料的方法。采用低温氮吸附、SEM和FT-IR手段表征了样品的比表面、颗粒形貌和表面基团;通过抑菌圈实验表征了样品对于金色葡萄球菌的抑制能力,并通过摇床实验表征了材料的耐溶出性能。研究发现本方法所制备的有机-无机杂化材料抗菌性能较好,并具有一定的耐溶出性能,有望作为缓释抗菌材料而应用于涂料或高分子材料中。

关键词: 抗菌性能, 二氧化硅, 苯扎溴铵, 耐溶出性

Abstract: Composite antibacterial materials were prepared via co-precipitation method with basic silica sol and dodecyl dimethyl benzyl ammonium chloride as raw materials.Low-temperature N2 adsorption,SEM,and FT-IR methods were employed to characterize the BET specific surface area,particle morphology,and surface functional groups of the as-made samples. Bacteriostasis circle experiments were conducted to assess the dissolving antibacterial performance of the samples upon staphylococcus aureus.Sustained-release ability of the as-made samples was investigated with dissolving experiment on rotary shaker.It was revealed by the results that as-made organic/inorganic composite antibacterial material show obvious antibacterial performance and good sustained-release ability.The composite materials are expected to be applied in paint or polymer as controlled-releasing antibacterial element.

Key words: antibacterial performance, silica, benzalkonium bromide, sustained-release

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