Abstract: The manganese-silver separation process，which uses plant by-product（straw and husk by-produced from grain processing etc.） as reducing agent for reduction leaching manganese in manganese-silver concentrate and for silver leaching from residue of manganese-leaching with cyanide was introduced.The conditions of corn straw reduction leaching manganese were as follows：straw powder pre-degradation and saccharification at 95 ℃ for 0.5 h，volume-mass ratio of degradation saccharification liquid to manganese-silver concentrate was 3 mL/g，amount of substance ratio-of-sulfuric acid to manganese was 1.4，mass ratio of straw to ore powder was 0.275，and leaching temperature and time were 95 ℃ and 5 h，respectively.The manganese leaching rate was about 92% under those conditions.Ag leaching rate of 92.20% could be achieved under the conditions when the dosage of NaCN was 3 kg per ton of the residue of manganese-leaching and the leaching temperature and time were room temperature and 3 h，respectively.The separation technology of manganese and silver had a very good comprehensive effect.

Key words: manganese-silver ore, plant by-product, reduction leaching of manganese, leaching silver from manganese slag