In order to develop high-performance dehumidification runner，through innovative material design and process optimization，silica gel matrix was deposited on cylindrical honeycomb carrier by in-situ growth technology，and magnesium sulfate（MgSO₄） was modified as hygroscopic salt.MgSO₄/silica gel composite honeycomb embryo was successfully prepared.By using single factor experiment method，the pretreatment conditions of carrier to enhance mechanical strength and the preparation conditions of composite dehumidification materials were systematically explored，and the optimal pretreatment slurry formula was determined as sodium silicate，polyvinyl alcohol（PVA），aluminum sol（solid ratio 1∶1∶1）.The optimal loading process conditions were determined by single factor experiment method as follows：the mass fraction of sodium silicate of 30%，impregnation for three times，acidification temperature of 90 ℃，the mass fraction of acid of 20%.The results of embryo adsorption test showed that with the increase of relative humidity from 50% to 80%，the moisture absorption of the sample was increased from 162 mg/g to 251 mg/g，increased by 54.93%，which was 2~3 times that of single silica gel.With the increase of temperature from 15 ℃ to 35 ℃，the adsorption equilibrium time of the sample was shortened from 835 s to 435 s，but the adsorption capacity was reduced from 256 mg/g to 133 mg/g.The increase of wind speed accelerated the adsorption rate and had little effect on the equilibrium adsorption capacity.The cyclic adsorption desorption experiments showed that the material had good cycling stability and renewability.