Efficient and clean comprehensive utilization of low and medium grade phosphate rock is a common bottleneck in the development of basic phosphorus chemical industry in China. Based on the pilot results of integrated comprehensive uti-lization of phosphorus-calcium-magnesium in low-grade phosphate rock,the high-quality phosphate concentrate [w（P₂O₅）≥36%, w（MgO）≤0.5%] can be obtained by directly treated of low and medium grade phosphate rock through innovative integrated technology,which can be used in any wet-process phosphoric acid and thermal yellow phosphorous production process,and the high value-added magnesium hydroxide and light calcium carbonate can be recovered simultaneously.All phosphorus in this process were recovered,and no tailings or waste water were discharged.The implementation of the project is of great sig-nificance to promote the sustainable development of China′s phosphorus chemical industry and solve the Three Phosphorus problem from the source.