The comprehensive extraction of lithium，potassium，rubidium and cesium from lepidolite concentrate by chlorina tion roastingwater leaching process was investigated.Through a series of conditions experiments including roasting tempera ture，roasting time，chlorinating agent amount and liquidsolid ratio etc.，the appropriate conditions were determined as fol lows：roasting temperature of 850 ℃，roasting time of 45 min，the amounts of anhydrous calcium chloride and sodium chloride are 50% of the amount of ore sample respectively，liquid solid mass ratio of 4 and leaching time of 45 min.Under the optimal conditions，the leaching rates of lithium，potassium，rubidium and cesium were 89.73%，90.64%，93.27% and 91.00%，respectively.In addition to high calcium content in leaching solution，other impurities such as magnesium，manganese，iron，aluminum and silicon etc.were rarely leached.The efficient separation of lithium，potassium，rubidium，cesium from the impurities was realized.