Abstract: <SPAN lang=EN-US style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体">According to the characteristics (containing indium,zinc,and manganese ions) of lixivium of simultaneously leaching pyrolusite and sphalerite in acidic conditions,indium was extracted and zinc and manganese were separated by P507 from lixivium.Influences of the factors,such as acidity (hydrogen ion concentration) of aqueous equilibrium<SPAN style="mso-spacerun: yes">&nbsp; </SPAN>phase,volume fraction of extractant,extraction temperature,volume ratio of organic phase to water phase,and extraction time on extractive efficiency of indium were investigated.Results showed a single extractive rate of indium was more than 99%,however,extractive rates of zinc and manganese were both less than 1.2% and the separation of indium with zinc and manganese achieved optimum effect under the conditions of room temperature,acidity of 2.5 mol/L,P507 volume fraction of 30% (30% P507+70% sulfonated kerosene),organic-water phase volume ratio of 1</SPAN><SPAN style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-bidi-font-size: 12.0pt; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA">∶</SPAN><SPAN lang=EN-US style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体">1,and time of 10 min.Loaded organic phase was washed with water and washing rate of zinc-manganese was 99% and indium was 0.Stripping with 2.0 mol/L hydrochloric acid,stripping rate of indium was more than 98%.Purpose of separation of zinc-manganese and enriching indium has achieved. </SPAN>