Abstract: Calcium sulfate whisker is a green environment-friendly material of excellent properties and low in price.It mainly abopts natural gypsum to produce calcium sulfate whisker,but natural gypsum is non-renewable resource.Therefore unlimited mining will lead to exhaustion of natural gypsum resources.There already has some researches on producing cal-cium sulfate whisker by using industrial by-product gypsum in China.Through expounding preparation principle of calcium sulfate whisker,and present situation of producing calcium sulfate whisker by using natural gypsum and industrial by-product gypsum,it was put forward that utilizing industrial by-product to prepare calcium sulfate whisker can protect natural gypsum resourse,as well as can realize resources regeneration,and it will be the future development tendency. 