Abstract:  By analyzing the economical efficiency of the differences of four methods of manufacturing activated zinc oxide，which are the acid method of adding soda（Na₂CO₃），the acid method of adding ammonium hydrogen carbonate （NH₄HCO₃），the ammonia leaching-ammonia distillation method（evaporating ammonia by heating），and carbonization method（by inletting carbon dioxide），it′s found that the alkali methods are superior to the acid methods，and the ammonia leaching-ammonia distillation method is the most cost-effective one.Acid methods have higher consumption costs of leaching reagent and synthesizing agent.Furthermore，the acid methods produce a large amount of wastewater during the manufacture process of activated zinc oxide.Since the treatment cost of wastewater is higher than the revenue of product recovery，their economical efficiency is poor. In conclusion，it is recommended to use the ammonia leaching-ammonia distillation method to manufacture activated zinc oxide，because it is not only economical，but also environmentally friendly.

Key words: activated zinc oxide, leaching cost, synthesis cost, wastewater treatment cost, product recovery