Abstract: <SPAN lang=EN-US style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体">Dispersion of nano-sized ZnO in water system and surface modification under this condition were studied.Orthogonal experiment was carried out to investigate the influences of dosages of dispersant and surface modifier as well as grinding speed and time on dispersion stability and surface modification effect of ZnO,with polyethylene glycol (PEG20000) and titanium ester coupling agent (NDZ) as dispersant and surface modifier.Results showed the optimum process conditions were:1) in the dispersion process</SPAN><SPAN style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-bidi-font-size: 12.0pt; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA">，</SPAN><SPAN style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体"> <SPAN lang=EN-US>w (PEG20000)=0.5%,and ball grinding speed and time were 2 000 r/min and 1 h,respectively;2) in the surface modification</SPAN></SPAN><SPAN style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-bidi-font-size: 12.0pt; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA">，</SPAN><SPAN style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体"> <SPAN lang=EN-US>w (NDZ)=1%,and ball grinding speed and time were 1 000 r/min and 1 h,respectively.Particle size and morphology of the product were characterized by laser particle size analyzer and SEM.Modified ZnO particles were smaller particles and effect of dispersion had improved obviously. </SPAN></SPAN>